Bhat R

Fernandes NC

Kandan S

Mariana Menezes

Mutasim DF

Nurimar Conceicao Fernandes

Pasricha JS

Sethy PK

Wanke NCF

Zivanovic D

Anais Brasileiros de Dermatologia

In this study, five cases of pemphigus vulgaris and two cases of pemphigus foliaceus were treated with cyclophosphamide pulse therapy associated with prednisone, resulting in the need for a smaller maintenance dose of prednisone. In three cases of pemphigus vulgaris and one case of pemphigus foliaceus, dexamethasone and cyclophosphamide pulse therapy associated with prednisone helped the lesions to heal more rapidly. Neither treatment however prevented the recurrence of the disease. Amenorrhea, myelotoxicity and Stevens-Johnson syndrome were among the cyclophosphamide side effects. All the patients treated with prednisone experienced known side effects.</jats:p

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Pulse therapy in pemphigus: report of 11 cases

http://www.scielo.br/pdf/abd/v88n4/0365-0596-abd-88-4-0672.pdf

Pulse therapy in pemphigus: report of 11 cases

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