Merkel cell carcinoma: from diagnosis to therapeutic management

Abstract

peer reviewedMerkel cell carcinoma is a skin malignancy showing an increasing trend of incidence in the white population. Its viral origin due to the MC polyomavirus is likely. The diagnosis relies on the histological and targeted immunopathological examinations. Histoprognostic criteria remain to be defined. An assessment using medical imaging is important to establish. Treatments rely on surgery and radiotherapy. Chemotherapy is mandatory at the metastatic stage. Some biotherapies are potentially active