Ha Thi Ngo

Inger-Lise Steffensen

Ragna Bogen Hetland

Unni Cecilie Nygaard

Journal of Obesity

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CorrigendumCorrigendum to (Genetic and Diet-InducedObesity Increased Intestinal Tumorigenesis in the DoubleMutant Mouse Model Multiple Intestinal Neoplasia X Obese viaDisturbed Glucose Regulation and Inflammation)Ha Thi Ngo, Ragna Bogen Hetland, Unni Cecilie Nygaard, and Inger-Lise SteffensenDepartment of Food, Water and Cosmetics, Division of Environmental Medicine, Norwegian Institute of Public Health,P.O. Box 4404 Nydalen, 0403 Oslo, NorwayCorrespondence should be addressed to Inger-Lise Steffensen; inger-lise.steffensen@fhi.noReceived 2 December 2015; Accepted 12 January 2016Copyright © 2016 HaThi Ngo et al. This is an open access article distributed under the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.In the published paper “Genetic and Diet-Induced ObesityIncreased Intestinal Tumorigenesis in the Double MutantMouse Model Multiple Intestinal Neoplasia X Obese via Dis-turbed Glucose Regulation and Inflammation” [1] wemistak-enly wrote IL-1𝛽 instead of IL-6 in Tables 2 and 3. In addition,IL-6 was not included in the text below the tables statingthat it was measured by flow cytometer as was TNF𝛼. Thecorrected tables are presented here.References[1] H. T. Ngo, R. B. Hetland, U. C. Nygaard, and I. Steffensen,“Genetic and diet-induced obesity increased intestinal tumori-genesis in the double mutant mouse model multiple intestinalneoplasia X obese via disturbed glucose regulation and inflam-mation,” Journal of Obesity, vol. 2015, Article ID 343479, 21pages, 2015.Hindawi Publishing CorporationJournal of ObesityVolume 2016, Article ID 2361290, 2 pageshttp://dx.doi.org/10.1155/2016/23612902 Journal of ObesityTable 2: Associations between various parameters for body weight and glucose, insulin and cytokine levels.AUC bw Terminal bw Terminal BMI𝑅2 𝑃 𝑅2 𝑃 𝑅2 𝑃Terminal bw 0.91 <0.001Terminal BMI 0.59 <0.001 0.62 <0.001Glucose 0.46 <0.001 0.47 <0.001 0.57 <0.0016 weeksGlucose 0.33 <0.001 0.33 <0.001 0.43 <0.00111 weeksInsulin 0.34 <0.001 0.32 <0.001 0.48 <0.001IL-6 0.00 n.s. 0.00 n.s. 0.01 n.s.TNF𝛼 0.20 0.021 0.23 0.013 0.07 n.s.Associations between various parameters for body weight (independent variables) and glucose, insulin, and cytokine levels (dependent variables) wereexamined with simple linear regression (SigmaPlot 12.3, Systat Software Inc., San Jose, CA, USA). This was performed on pairs of end points from all micefrom all experimental groups from which individual data could be paired. Body weight (bw) data were evaluated either as area under the curve from week 3 toweek 11 (AUC bw), as terminal bw, or as terminal body mass index (BMI) at 11 weeks of age. Nonfasted blood glucose was measured at 6 and 11 weeks of age.Insulin was measured with ELISA, and IL-6 and TNF𝛼 were measured with flow cytometer, all in plasma obtained at termination at 11 weeks. 𝑅2 = coefficientof determination, n.s. = not statistically significant.Table 3: Associations between body weight, glucose, insulin and cytokine levels and the number or diameter of small intestinal tumors.Number of small intestinal tumors Diameter of small intestinal tumors𝑅2 𝑃 𝑅2 𝑃Diameter of tumors 0.51 <0.001 No. of tumors 0.51 <0.001AUC bw 0.11 <0.001 AUC bw 0.14 <0.001Terminal bw 0.05 <0.001 Terminal bw 0.07 <0.001Terminal BMI 0.08 <0.001 Terminal BMI 0.10 <0.001Glucose 0.12 <0.001 Glucose 0.09 <0.0016 weeks 6 weeksGlucose 0.18 <0.001 Glucose 0.08 <0.00111 weeks 11 weeksInsulin 0.03 n.s. Insulin 0.06 n.s.IL-6 0.00 n.s. IL-6 0.01 n.s.TNF𝛼 0.09 n.s. TNF𝛼 0.31 0.003Associations between body weight parameters, glucose, insulin, and cytokine levels (independent variables) and the number or diameter of small intestinaltumors (dependent variables) were examined with simple linear regression (SigmaPlot 12.3, Systat Software Inc., San Jose, CA, USA). This was performed onpairs of end points from all mice from all experimental groups from which individual data could be paired. Number of small intestinal tumors is calculatedas number of tumors in each mouse, and tumor diameter is calculated as mean of all tumors in each mouse. Body weight (bw) data were evaluated either asarea under the curve from week 3 to week 11 (AUC bw), as terminal bw, or as terminal body mass index (BMI) at 11 weeks of age. Nonfasted blood glucosewas measured at 6 and 11 weeks of age. Insulin was measured with ELISA, and IL-6 and TNF𝛼 were measured with flow cytometer, all in plasma obtained attermination at 11 weeks. 𝑅2 = coefficient of determination, n.s. = not statistically significant.Submit your manuscripts athttp://www.hindawi.comStem CellsInternationalHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Hindawi Publishing Corporationhttp://www.hindawi.com Volume 2014MEDIATORSINFLAMMATIONofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Behavioural NeurologyEndocrinologyInternational Journal ofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Hindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Disease MarkersHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014BioMed Research InternationalOncologyJournal ofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Hindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Oxidative Medicine and Cellular LongevityHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014PPAR ResearchThe Scientific World JournalHindawi Publishing Corporation http://www.hindawi.com Volume 2014Immunology ResearchHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Journal ofObesityJournal ofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Hindawi Publishing Corporationhttp://www.hindawi.com Volume 2014 Computational and  Mathematical Methods in MedicineOphthalmologyJournal ofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Diabetes ResearchJournal ofHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Hindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Research and TreatmentAIDSHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Gastroenterology Research and PracticeHindawi Publishing Corporationhttp://www.hindawi.com Volume 2014Parkinson’s DiseaseEvidence-Based Complementary and Alternative MedicineVolume 2014Hindawi Publishing Corporationhttp://www.hindawi.com

Corrigendum to “Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation”

Corrigendum to “Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation”

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