Abadie JJ

Kiupel M

Koss LG

Kravis LD

Marchevsky AM

Prophet EB

Tyler RD

 Twenty-nine canine cutaneous mast cell tumors (MCTs) were morphometrically analyzed with regard to mean nuclear area (MNA) using cytopathology smears. The results showed a correlation between MNA and survival. When graded into 2 morphometrically different groups, there were statistically significant differences among high- and low-grade MCTs, regarding both Romanowsky-type stain and hematoxylin and eosin. Cytomorphometry could also separate histologic grade II tumors with better prognosis from the more aggressive MCTs. The results indicated that nuclear morphometry on cytopathology preparations can predict the biological behavior of cutaneous MCTs in dogs in an independent manner, yielding a rapid and reproducible diagnosis, which renders the method useful for veterinary oncology. </jats:p

Ricardo Francisco De Strefezzi

José Guilherme Xavier

Silvia Regina Kleeb

José Luiz Catão-Dias

Crossref

Journal of Veterinary Diagnostic Investigation

Nuclear Morphometry in Cytopathology: A Prognostic Indicator for Canine Cutaneous Mast Cell Tumors

Nuclear Morphometry in Cytopathology: A Prognostic Indicator for Canine Cutaneous Mast Cell Tumors

Abstract

Similar works

Full text

Available Versions

Crossref