Borah PK

Hazarika NC

Kawamoto K

Manimunda SP

Mohan V

Roy SK

Shanthirani CS

Shojania KG

Thankappan KR

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease


            Background
            Randomized control trials from the developed world report that clinical decision support systems (DSS) could provide an effective means to improve the management of hypertension (HTN). However, evidence from developing countries in this regard is rather limited, and there is a need to assess the impact of a clinical DSS on managing HTN in primary health care center (PHC) settings.
          
          
            Methods and Results
            
              We performed a cluster randomized trial to test the effectiveness and cost‐effectiveness of a clinical DSS among Indian adult hypertensive patients (between 35 and 64 years of age), wherein 16 PHC clusters from a district of Telangana state, India, were randomized to receive either a DSS or a chart‐based support (CBS) system. Each intervention arm had 8 PHC clusters, with a mean of 102 hypertensive patients per cluster (n=845 in DSS and 783 in CBS groups). Mean change in systolic blood pressure (SBP) from baseline to 12 months was the primary endpoint. The mean difference in SBP change from baseline between the DSS and CBS at the 12th month of follow‐up, adjusted for age, sex, height, waist, body mass index, alcohol consumption, vegetable intake, pickle intake, and baseline differences in blood pressure, was −6.59 mm Hg (95% confidence interval: −12.18 to −1.42;
              P
              =0.021). The cost‐effective ratio for CBS and DSS groups was $96.01 and $36.57 per mm of SBP reduction, respectively.
            
          
          
            Conclusion
            Clinical DSS are effective and cost‐effective in the management of HTN in resource‐constrained PHC settings.
          
          
            Clinical Trial Registration
            
              URL:
              http://www.ctri.nic.in
              . Unique identifier: CTRI/2012/03/002476.
            
          </jats:sec

Raghupathy Anchala

Stephen Kaptoge

Hira Pant

Emanuele Di Angelantonio

Oscar H. Franco

D. Prabhakaran

Crossref

Journal of the American Heart Association

Evaluation of Effectiveness and Cost‐Effectiveness of a Clinical Decision Support System in Managing Hypertension in Resource Constrained Primary Health Care Settings: Results From a Cluster Randomized Trial

Evaluation of Effectiveness and Cost‐Effectiveness of a Clinical Decision Support System in Managing Hypertension in Resource Constrained Primary Health Care Settings: Results From a Cluster Randomized Trial

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