Varying the load during a back squat exercise using chains in combination with free-weight resistance (FWR) will manipulate the loading characteristics of the lift. Consequently, this may alter neuromuscular demand and induce post-activation potentiation (PAP). Preconditioning the muscle using near maximal or maximal voluntary contractions can increase force production and improve subsequent strength performance, however the influence of chain-loaded resistance (CLR) on subsequent free-weight squat performance has not been examined. Thus, the aim of the present study was to determine the effects of a chain-loaded resistance warm-up routine on subsequent free-weight squat performance