A Fiore Di

A Theodossis

AN Bigley

B Hofmann

B Siebers

BM Nestl

C Sayer

C Upton

CM Waters

DL Ollis

DL Yin

DM Blow

DN Silverman

E Ferrandi

E Porzio

EE Ferrandi

G Höst

G Manco

G Simone De

GB Slobodkina

HJ Lamble

HS Toogood

J Bains

J Hiblot

J Kim

J Littlechild

J. A. Littlechild

JD Cheeseman

JE Guy

K Line

KH Hopmann

Klenk Hans-Peter

KO Stetter

KS Smith

L Afriat

L Merone

LV Rao

M Arand

M Kotik

M Nardini

M Reher

M Singleton

M Widersten

MI Prokofeva

MJ Danson

MJ Kirisits

MN Isupov

N Lenfant

OO Guler

P Bernhardt

P James

P Mallick

PC Bourne

R Jaenicke

R Sharma

R Sinha

R Wohlgemuth

RD Finn

RM Daniel

S Baxter

S Bencharit

S Lindskog

S McNicholas

SB Kim

TR Kievit De

UG Wagner

UT Bornscheuer

V Kallnik

VM Gumerov

WL DeLano

X-D Kong

Abstract
               The speed of sequencing of microbial genomes and metagenomes is providing an ever increasing resource for the identification of new robust biocatalysts with industrial applications for many different aspects of industrial biotechnology. Using ‘natures catalysts’ provides a sustainable approach to chemical synthesis of fine chemicals, general chemicals such as surfactants and new consumer-based materials such as biodegradable plastics. This provides a sustainable and ‘green chemistry’ route to chemical synthesis which generates no toxic waste and is environmentally friendly. In addition, enzymes can play important roles in other applications such as carbon dioxide capture, breakdown of food and other waste streams to provide a route to the concept of a ‘circular economy’ where nothing is wasted. The use of improved bioinformatic approaches and the development of new rapid enzyme activity screening methodology can provide an endless resource for new robust industrial biocatalysts.This mini-review will discuss several recent case studies where industrial enzymes of ‘high priority’ have been identified and characterised. It will highlight specific hydrolase enzymes and recent case studies which have been carried out within our group in Exeter.</jats:p

J A Littlechild

Crossref

Journal of Industrial Microbiology & Biotechnology

Improving the ‘tool box’ for robust industrial enzymes

https://link.springer.com/content/pdf/10.1007%2Fs10295-017-1920-5.pdf

Improving the ‘tool box’ for robust industrial enzymes

Abstract

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