Influence of Bioimplant Surface Electrical Potential on Osteoblast Behavior and Bone Tissue Formation

Abstract

Following the general adhesion theory the bone cells attachment to the bioimplant could be controlled by its surface electrical potential. The latter was adjusted both by deposition of the electrical charge and the surface microgeometry. It was demonstrated that a relief of the surface had an influence on the potential at the nanoscale and could be engineered to promote cell adhesion. Both deposition of the charge and engineering of the potential demonstrated influence on human osteoblast attachment and bone tissue formation. The surface areas of the electrical potential demonstrated a correlation length effecting fabrication of the bone tissue.