This thesis describes the synthesis of natural and novel glucosinolates 1.Chapter 1 gives an overview of glucosinolates, from isolation and biosynthesis
to previous chemical syntheses. Chapter 2 describes an improved method for
the formation of thiohydroximate bonds and its application over a variey of
substrates. Chapter 3 focuses on exploring new chemistry on intact glucoinolates and details oxidative chemistry on an alkene containing side chain glucosinolate. Futhermore, the total synthesis of novel glucosinolates 150, 156 and 161 is illustrated.Chapter 4 describes a model study for the solid phase synthesis of
glucosinolates. Finally experimental procedures for the compounds synthesised
in the thesis are described in Chapter 5
