Paper presented at the 2006 IEEE 32nd Annual Northeast Bioengineering Conference Easton, PA. DOI: http://dx.doi.org/10.1109/ROBOT.2006.1641779Tissue scaffolds must satisfy multiple design constraints, such as geometry, mechanical properties, and connectivity, to yield a functioning heterogeneous tissue. One method that accounts for these multiple constraints is the unit-cell based assembly approach. In this method, the volume that represents the natural tissue is filled with unit-cells that meet the design requirements of the volume. This approach requires data exchanges between several procedures including design, characterization, assembly, analysis, and fabrication procedures. In the paper, we present a data exchange system to store and retrieve the unit-cell information and customize data migration among applications. We also present our application of this data exchange system to facilitate the management of data flow