The purposes of this research were to know: 1) the influence of Everyone is
a Teacher Here to the mastery of biology result 2) the influence of student’s learning interest
to the mastery of biology result; 3) the interaction between learning model and learning
interest to the mastery of biology result ; and 4) the influence of better learning model to the
mastery of biology result This research was quasi experiment research using Randomized
Control Only design. Learning model and learning interest were independent variables and
mastery of biology concept was the dependent variable. The population of this research was
all of X grade of SMA Negeri 1 Sukoharjo. The samples of this research were the students of
class XI IPA 2 as the control class and students of class XI IPA 6 as the experimental class.
The sample of this research was established by cluster random sampling. The data about the
result of study biology collected by use test and observation. Learning interest meansured by
using questionnaires. The analisis of this research was anava two away in different cell and
the advance test used Bonfferoni test. . The conclusion of this research were: 1) Problem
Based Instruction had significant influence to the mastery of biology result kognitif domain
on XI IPA grade of SMA Negeri 1 Sukoharjo; 2) Learning interest hadn’t significant
influence to the mastery of biology result kognitif domain on XI IPA grade of SMA Negeri 1
Sukoharjo; and 3) There wasn’t interaction between learning model and learning interest to
the mastery of biology result kognitif domain on XI IPA grade of SMA Negeri 1 Sukoharj
