In this thesis, I summarized results from researches done during my PhD course, organizing them in a brief introduction and five chapters. Specifically, the first chapter of this work is dedicated to the progress made during the past years in neuroimaging technologies and techniques, with a focus on structural Magnetic Resonance Imaging techniques and their employment into the neuropsychiatric research.
The following three chapters are dedicated to the three studies, all developed though a specific research topic and directed to the understanding of the neural basis of Bipolar Disorder and its clinical implications
