The Chronic Kidney Disease (CKD) is a kidney dysfunction for which the estimated Glomerular Filtration Rate (eGFR) result

A. Montaruli

E. Roveda

F. Carandente

J.A. Vitale

L. Caldiroli

L. Galasso

L. Montagna

S. Vettoretti

AIR Universita degli studi di Milano

IJAE 
Vo l .  121,  n .  1  (Supp lem ent) :  20 0,  2016
© 2016 Firenze University Press 
ht tp://www.fupress .com/ijae
ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY
Anthropometric indices of sarcopenia in patients with 
Chronic Kidney Disease 
Letizia Galasso 1 - Lorenzo Montagna 2 - Jacopo Antonino Vitale 3 - Simone Vettoretti 2 - Lara 
Caldiroli 2 - Eliana Roveda 1 - Franca Carandente 1 - Angela Montaruli 1
1 Università degli Studi di Milano, Dipartimento delle Scienze Biomediche per la Salute, Milano, Italia – 2 
IRCCS, Cà Granda Ospedale Maggiore Policlinico, U.O. di Nefrologia e Dialisi, Milano, Italia – 3 IRCCS, Istituto 
Ortopedico Galeazzi, Milano, Italia
The Chronic Kidney Disease (CKD) is a kidney dysfunction for which the esti-
mated Glomerular Filtration Rate (eGFR) results <90 ml/min. The primary causes 
are glomerulonephritis, nephrosclerosis, diabetic nephropathy, nephropathy due to 
obesity and unilateral kidney (1). CKD is associated with frailty, cardiovascular dis-
ease, hypokinesia, sarcopenia and disability (2). In this study participated 74 subjects 
with CKD (mean age ≥ 65 years), 45 males and 29 females. All subjects underwent 
to anthropometric measurements: height, weight, BMI, circumferences (waist, domi-
nant wrist, right/left arm, right/left thigh, right/left leg), body folds (biceps right/
left, triceps right/left), calculation of the arm areas (adipose area, lean area, total area 
and muscle circumference). We divided the subjects into 5 samples according to the 
classification of Walker (2) based on the eGFR (ml/min): stage I+II (n=1), stage III 
(n=14) stage IV (n=50) stage V (n=9). In particular we have taken into account the 
anthropometric data of the stage III and V: BMI (stage III 28.85 ± 6.2 vs stage V 26.47 
± 3.69); total arm area (stage III 72.33 ± 16.52 vs stage V 65.36 ± 18.1); muscle arm 
circumference (stage III 26.06 ± 3.05 vs stage V 24.46 ± 3.52); adipose arm area (stage 
III 16.80 ± 7.94 vs stage V 16.58 ± 6.39); lean arm area (stage III 55.37 ± 13.68 vs stage 
V 48.90 ± 15.09). These preliminary results show that there is a worsening trend in 
anthropometric data according to the disease progression, from III to V stage, though 
the statistical analysis did not reach the significance. 
References
[1] Hamada et al. (2015) The effectiveness and safety of modest exercise in Japanese patients with 
chronic kidney disease: a single-armed interventional study. Clin Exp Nephrol; DOI:10.1007/
s10157-015-1147-6.
[2] Walker et al. (2015) Frailty and physical function in chronic kidney disease: the CanFIT study. 
Canadian Journal of Kidney Health and Disease; (2):32; DOI 10.1186/s40697-015-0067-4.
Keywords
Chronic kidney disease; eGFR; anthropometry.


Anthropometric indices of sarcopenia in patients with Chronic Kidney Disease

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