We present a case of severe, irreversible neurotoxicity in a 55-year-old-patient
with myelofibrosis undergoing hematopoietic stem cell transplantation following
a reduced intensity conditioning including fludarabine. The patient developed
progressive sensory-motor, visual and consciousness disturbances,
eventually leading to death. MRI imaging pattern was unique and attributable
to fludarabine neurotoxicit
