Bosmans, Johan

Collas, Val\ue9rie

De Bruyne, Bernard

Dens, Jo

Dubois, Christophe

Herijgers, Paul

Kefer, Jo\ueblle

Legrand, Victor

Rodrigus, Inez

Abstract: Objective To assess midterm (3 years) clinical outcomes of transcatheter aortic valve implantation (TAVI) in Belgium using the Edwards SAPIEN valve or the Medtronic CoreValve transcatheter heart valve (THV). Background Medium and long term follow-up data of both THVs are still relatively scarce, although of great clinical relevance for a relatively new but rapidly expanding treatment modality. Therefore, reporting mid- and long term clinical outcome data, coming from large real world national registries, remains contributive. Methods Between December 2007 and March 2012, 861 real world patients who were not candidates for surgical aortic valve replacement as decided by the local heart teams, underwent TAVI at 23 sites. Eleven sites exclusively used SAPIEN THV (n\u2009=\u2009460), while 12 exclusively used CoreValve THV (n\u2009=\u2009401). Differences in clinical outcomes by valve system were assessed, according to access route and baseline EuroSCORE risk profile (20%: high risk). Results Overall cumulative survival at 3 years was 51% for SAPIEN vs. 60% for CoreValve (P\u2009=\u20090.021). In transfemorally treated patients, SAPIEN and CoreValve had similar survival at 3 years for each of the baseline EuroSCORE cohorts (low risk: 72% vs. 76%, P\u2009=\u20090.45; intermediate risk: 62% vs. 59%, P\u2009=\u20090.94; high risk: 48% vs. 53%, P\u2009=\u20090.65). Conclusion Cumulative midterm 3 year survival after transfemoral TAVI in real world patients refused for surgery with similar baseline EuroSCORE risk profile is not different between SAPIEN or CoreValve

Institutional Repository Universiteit Antwerpen

Midterm clinical outcome following Edwards SAPIEN or Medtronic Corevalve transcatheter aortic valve implantation (TAVI) : results of the Belgian TAVI registry

Midterm clinical outcome following Edwards SAPIEN or Medtronic Corevalve transcatheter aortic valve implantation (TAVI) : results of the Belgian TAVI registry

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Institutional Repository Universiteit Antwerpen