Beutels, Philippe

Bilcke, Joke

Abstract: This study reviews published health economic evaluations of rotavirus vaccination up until July 2008. We assess whether differences in the results and conclusions of the various studies are due to differences in methodological and modelling choices, and/or the way parameter uncertainty was taken into account, or whether these are merely the result of genuine country/region-specific differences. No unambiguous single answer emerged for the question of whether universal rotavirus vaccination is or is not cost effective. The relevance and merits of each study need to be assessed within its context. This is illustrated by the fact that comparisons of different analyses for a single country show

Reviewing the cost-effectiveness of rotavirus vaccination: the importance of uncertainty in the choice of data sources

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