Araki, Hiroshi

Kamiyama, Yasuo

Komemushi, Atsushi

Matsui, Yoichi

Mergental, Hynek

Satoi, Sohei

Takai, Soichiro

Tanigawa, Noboru

Toyokawa, Hideyoshi

Yanagimoto, Hiroaki

BACKGROUND/AIMS: Accurate pre-operative staging in patients with pancreatic cancer is crucial for avoiding unnecessary laparotomy and for selecting patients accurately for curative resection. In this study, tumor resectability and residual tumor grading in patients evaluated by MD-CT (Multi-detector row CT) or by SD-CT (single-detector CT) were compared to determine whether more accurate imaging has a significant clinical impact on patient selection and surgical outcomes.METHODOLOGY: One hundred-fifty consecutive patients with pancreatic cancer evaluated from January 2000 to April 2005 were included in this retrospective study. Seventy pancreatic cancer patients underwent pre-operative evaluation using SD-CT and angiography (5-7 mm slice thickness, 1st period 2000-2002), and 80 patients underwent MD-CT (1.25 mm slice thickness, 2nd period 2002-2005).RESULTS: The introduction of MD-CT had a significant impact on the selection of suitable patients, this group showing a lower frequency of surgical intervention in cases of incurable disease (p = 0.0383). Pre-operative evaluation using MD-CT in the resected cases also provided a higher percentage of accurate R0/R1 grading relative to SD-CT evaluations (p = 0.0164).CONCLUSION: MD-CT imaging has a significant impact on preventing unnecessary exploratory surgery and on the selection of appropriate pancreatic cancer patients for surgical resection.</p

University of Birmingham Research Portal

Pre-operative patient selection of pancreatic cancer patients by multi-detector row CT

Pre-operative patient selection of pancreatic cancer patients by multi-detector row CT

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University of Birmingham Research Portal

University of Birmingham Research Portal