"October 2002"Bibliography: leaves 159-198.xiv, 198 leaves : ill. (some col.) ; 30 cm.This thesis describes the mapping of the breakpoints of three different chromosome rearrangements, all involving 1p36, in acute myeloid leukaemia (AML) patients, and an investigation into the molecular outcomes of these rearrangements.Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 200