Figure S3. Mean Spearman correlation between raw and normalized counts. Spearman correlations were compute per gene before and after normalization in the Human gut I, for group size 10+10, with 10% of effects divided equally between the two group, and fold-change 3. Affected genes were randomly selected in 100 iterations. The following methods are included in the figure trimmed mean of M-values (TMM), relative log expression (RLE), cumulative sum scaling (CSS), reversed cumulative sum scaling (RCSS), quantile-quantile (Quant), upper quartile (UQ), median (Med), total count (TC) and rarefying (Rare). (PDF 8 kb