Aim: There is a paucity of information about changes in splenic volume after surgery. The aim of this study was to investigate postoperative changes in splenic volume(SV)and the factors influencing SV after spleen-preserving distal pancreatectomy(SPDP)with conservation of the splenic artery and vein (CSAV), and after surgery of the digestive tract and breast.Methods: We investigated 113 patients who underwent SPDP with CSAV(n=7), breast surgery (n=24), colorectal surgery(n=45), distal gastrectomy(n=27)and total gastrectomy(n=10). SV changes were determined for three years after surgery using volumetry based on computed tomographic imaging, and splenic vein diameter changes after SPDP with CSAV were also determined.Results: Splenic vein diameter after SPDP with CSAV did not change during 3 years. SV did not change significantly during 3 years after SPDP with CSAV and distal gastrectomy. After breast and colorectal surgery, and total gastrectomy, SV was decreased.Conclusions: Postoperative SV changes differed according to the type of surgery. SV did not change significantly during 3 years after SPDP with CSAV