Antibacterial and antifungal activity of the liverwort (Ptilidium pulcherrimum) methanol extract
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Abstract
The antimicrobial activity of the methanol extract from the liverwort, Ptilidium pulcherrimum was evaluated against five bacterial and six fungal species. In vitro antibacterial activity was assessed by disc diffusion and microdilution methods. The extract showed a stronger effect against tested Gram (+) than Gram (-) bacteria. The antifungal activity of the methanol extract was tested using a microdilution method. The methanol extract showed strong antifungal activity. The best antifungal activity was achieved against Trichoderma viride compared to the synthetic fungicide bifonazol.Antibakterijsko i antifungalno dejsto metanolnog ekstrakta jetrenjače Ptilidium pulcherrimum ispitivano je na 5 vrsta bakterija i 6 mikromiceta. Za ispitivanje in vitro antimikrobnog dejstva ekstrakta korišćena je metoda mikrodilucije na mikrotitracionim pločama i metoda difuzije sa filter diskova. Ekstrakt je pokazao jači efekat na testirane Gram (+), nego na Gram (-) bakterije. Antifungalna aktivnost metanolnog ekstrakta ispitana je mikrodilucionom metodom. Testirani ekstrakt pokazao je jak antifungalni potencijal na Trichoderma viride, Bifonazol je pokazao skoro identičnu fungistatičku aktivnost, dok je njegova fungicidna aktivnost bila nešto viša u poređenju sa metanolnim ekstraktom analizirane jetrenjače.Projekat ministarstva br. 143049 i 14304