Immunological and virological investigations arising from the 2007 Australian equine influenza outbreak

Abstract

© 2016 Dr. Charles Mark El-HageDuring Australia’s equine influenza (EI) outbreak, horses were vaccinated in Victoria prophylactically using a recombinant canarypox- vectored vaccine. Humoral and cell–mediated immune responses were monitored following an accelerated primary course reduced to 14 days. To demonstrate proof of freedom from EI, nasal swabs were taken from diseased and normal horses. Quantitative PCR was performed on samples from 559 horses, all negative for EI. Shedding of equine herpesviruses -1,-2 and -4 was correlated with the horse’s clinical status