Moghbeli Hanza, Fateme

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        داﻧﺸﮕﺎه ﻋﻠﻮم ﭘﺰﺷﻜﻲ ﻛﺮﻣﺎن  داﻧﺸﻜﺪه ﭘﺰﺷﻜﻲ  ﭘﺎﻳﺎن ﻧﺎﻣﻪ دوره ﭘﺰﺷﻜﻲ ﻋﻤﻮﻣﻲ   ﻋﻨﻮان:ﺑﺮرﺳﻲ ﻓﺮاواﻧﻲ ﺿﺎﻳﻌﺎت ﭘﻮﺳﺘﻲ درﺑﻴﻤﺎران ﺑﺎ ﺑﻴﻤﺎري  ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ  ﻣﺮاﺟﻌﻪ   6931-0931ﻛﻨﻨﺪه ﺑﻪ اﺗﺎق ﻋﻤﻞ ﭘﻮﺳﺖ ﺑﻴﻤﺎرﺳﺘﺎن اﻓﻀﻠﻲ ﭘﻮر ﻛﺮﻣﺎن از ﺳﺎل   ﺗﻮﺳﻂ:  ءﻓﺎﻃﻤﻪ ﻣﻘﺒﻠﻲ ﻫﻨﺰا  اﺳﺘﺎد راﻫﻨﻤﺎ:   ﻣﻬﻴﻦ اﻓﻼﻃﻮﻧﻴﺎندﻛﺘﺮ   اﺳﺎﺗﻴﺪ ﻣﺸﺎور :   دﻛﺘﺮ ﻣﺮﻳﻢ ﺧﻠﻴﻠﻲ ، دﻛﺘﺮ ﺳﻤﻴﻤﻦ ﺷﻤﺴﻲ ﻣﻴﻤﻨﺪي و دﻛﺘﺮ رﺿﻮان اﻣﻴﺮي   ﺳﺎل ﺗﺤﺼﻴﻠﻲ:  69-79  ﺑﻴﻤﺎران ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ ﻣﺮاﺟﻌﻪ ﻛﻨﻨﺪه ﺑﻪ  ﺗﻌﻴﻴﻦ ﻓﺮاواﻧﻲ ﺿﺎﻳﻌﺎت ﭘﻮﺳﺘﻲ دراﻳﻦ ﭘﮋوﻫﺶ ﺑﺎ ﻫﺪف  زﻣﻴﻨﻪ و ﻫﺪف:   6931-0931اﺗﺎق ﻋﻤﻞ ﭘﻮﺳﺖ ﺑﻴﻤﺎرﺳﺘﺎن اﻓﻀﻠﻲ ﭘﻮر ﻛﺮﻣﺎن از ﺳﺎل در اﺑﺘﺪا ﺑﻴﻤﺎر اﻧﺠﺎم ﮔﺮدﻳﺪ .  882ﺗﺤﻠﻴﻠﻲ  ﺑﻮد ﻛﻪ ﺑﺮ روي  -اﻳﻦ ﻣﻄﺎﻟﻌﻪ ﻣﻘﻄﻌﻲ از ﻧﻮع ﺗﻮﺻﻴﻔﻲ  ﻣﻮاد و روش ﻫﺎ:، ﺳﭙﺲ ﺧﺼﻮﺻﻴﺎت ﻛﻠﻴﻨﻴﻜﻲ  ﮔﺮدﻳﺪ، ﺟﻨﺲ در ﭼﻚ ﻟﻴﺴﺖ ﺛﺒﺖ  ﻣﺸﺨﺼﺎت دﻣﻮﮔﺮاﻓﻴﻚ ﺑﻴﻤﺎران ﺷﺎﻣﻞ ﺳﻦ و ...( ، رﻧﮓ ﺿﺎﻳﻌﻪ )ﻮع ﻛﻠﻴﻨﻴﻜﻲ ﺿﺎﻳﻌﻪ ) ﭘﺎﭘﻮل، ﭘﻼك ، ﻧ ، ﻣﺤﻞ ﺿﺎﻳﻌﻪ ﺿﺎﻳﻌﻪ ﭘﻮﺳﺘﻲ ﺷﺎﻣﻞ ﻃﻮل ﻣﺪت اﺑﺘﻼ. ﻧﻬﺎﻳﺘﺎ  ﮔﺮدﻳﺪ ﺗﺸﺨﻴﺺ ﻧﻬﺎﻳﻲ ( ﺛﺒﺖ ) ﺑﺮداري( و ﻣﺸﺨﺼﺎت ﻧﻤﻮﻧﻪ ﻗﺮﻣﺰ، ﺑﻨﻔﺶ، ﻫﺎﻳﭙﺮ ﻳﺎ ﻫﺎﻳﭙﻮﭘﻴﮕﻤﺎﻧﺘﻪﺎﺗﻮﻟﻮژﻳﺴﺖ و ﺗﺸﺨﻴﺺ ﻧﻬﺎﻳﻲ ﮔﺬاﺷﺘﻪ ﺷﺪه ﺗﻮﺳﻂ ﭘﺎﺗﻮﻟﻮژﻳﺴﺖ ﻫﻤﺒﺴﺘﮕﻲ ﻣﺜﺒﺖ ﺑﻴﻦ ﺗﺸﺨﻴﺺ اﻓﺘﺮاﻗﻲ ﻣﺪ ﻧﻈﺮ درﻣ  . ﮔﺮدﻳﺪﻧﺪ ﺗﺤﻠﻴﻞ ssps52آﻣﺎري ﻧﺮم اﻓﺰار از اﺳﺘﻔﺎده ﺑﺎ ﻫﺎ ﺑﺮرﺳﻲ ﮔﺮدﻳﺪ و دادهﻧﺘﺎﻳﺞ ﭘﮋوﻫﺶ ﻓﻮق ﻧﺸﺎن داد ﻛﻪ ﺷﺎﻳﻊ ﺗﺮﻳﻦ ﺑﻴﻤﺎري ﻫﺎي ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ در ﺷﺮﻛﺖ ﻛﻨﻨﺪﮔﺎن ﺣﺎﺿﺮ در ﻳﺎﻓﺘﻪ ﻫﺎ: ﺷﺎﻳﻊ ﺗﺮﻳﻦ ﮔﺮوه ﺳﻨﻲ ﻣﺒﺘﻼ ﺑﻴﻤﺎري ﻫﺎي ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ  17/ 4ﺑﺎ درﺻﺪ ﻓﺮوان  ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪﭘﮋوﻫﺶ ،  ( % 46/ 5)  ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪ. از ﻟﺤﺎظ ﺟﻨﺴﻴﺖ ﻣﻴﺰان ﻓﺮاواﻧﻲ  ( ﻣﻲ ﺑﺎﺷﺪ % 42/ 2 ﺳﺎل )  06ﺗﺎ  05( و  % 88/ 8 ) اﺳﻜﻠﺮوزﻳﺲ ﺳﻴﺴﺘﻤﺴﻚ % ( 18) ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ ﺳﻴﺴﺘﻤﻴﻚ،  ( %  57/ 7 ) ﻟﻴﻜﻦ اﺳﻜﻠﺮوزﻳﺲ. از ﻟﺤﺎظ ﻣﺪت  ( در ﺟﻨﺲ ﻣﻮﻧﺚ ﺑﻴﺸﺘﺮ از ﻣﺬﻛﺮ ﺑﻮد %  06) ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ ﺗﺤﺖ ﺣﺎد،  ( % 86/ 7 ) ﻣﻮرﻓﻪ آ 6( در ﻣﺪت زﻣﺎن ﻛﻤﺘﺮ از  % 86)  ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪﺑﻴﻤﺎري ﺷﺎﻳﻊ ﺗﺮﻳﻦ اﺧﺘﻼل ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ ﻣﺮﺑﻮط ﺑﻪ  در ﺳﺮ وﮔﺮدن ) ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪط . از ﻟﺤﺎظ ﻣﺤﻞ ﺑﻴﻤﺎري ﺷﺎﻳﻊ ﺗﺮﻳﻦ اﺧﺘﻼل ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ ﻣﺮﺑﻮ ﻣﺎه ﺑﻮدﺑﻪ  ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪ. از ﻟﺤﺎظ رﻧﮓ ﺑﻴﻤﺎري ﺷﺎﻳﻊ ﺗﺮﻳﻦ اﺧﺘﻼل ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ ﻣﺮﺑﻮط  ( ﺑﻮد % 29/ 7ﻟﻮﭘﻮس . از ﻟﺤﺎظ ﻛﻠﻴﻨﻴﻚ ﺑﻴﻤﺎري ﺷﺎﻳﻊ ﺗﺮﻳﻦ اﺧﺘﻼل ﺑﺎﻓﺖ ﻫﻤﺒﻨﺪ ﻣﺮﺑﻮط  ( ﺑﻮد % 75/ 3 ﺻﻮرت اﻳﺘﺮوﻣﺎﺗﻴﻮ ). ﻫﻤﭽﻨﻴﻦ درﺻﺪ ﻓﺮاواﻧﻲ ﻣﻮارد اﻧﻄﺒﺎق ﺑﻴﻦ ﺗﺸﺨﻴﺺ ﻫﺎي  ( ﺑﻮد % 26/ 9ﺑﻪ ﺻﻮرت ﭘﻼك ) ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪﺑﺮاي % (  54/ 6 ) ﻟﻮﭘﻮس ﭘﻮﺳﺘﻲ دﻳﺴﻜﻮﺋﻴﺪﻧﻬﺎﻳﻲ و ﺗﺸﺨﻴﺺ اﻓﺘﺮاﻗﻲ اول ﺗﻮﺳﻂ درﻣﺎﺗﻮﻟﻮژﻳﺴﺖ ﺑﺮاي ﺑﺮاي  % ( 72/ 2)  ﻟﻴﻜﻦ اﺳﻜﻠﺮوزﻳﺲﺑﺮاي  % ( 65/ 2)  ﻣﻮرﻓﻪ آﺑﺮاي  (  % 88/ 8 ) اﺳﻜﻠﺮوزﻳﺲ ﺳﻴﺴﺘﻤﺴﻚﺳ ﻲﺘﺳﻮﭘ سﻮﭘﻮﻟﻚﻴﻤﺘﺴﻴ  )8 /81  ( % ياﺮﺑدﺎﺣ ﺖﺤﺗ ﻲﺘﺳﻮﭘ سﻮﭘﻮﻟ  )60 ( %  ياﺮﺑسوﺪﻴﻣﻮﺗ سﻮﭘﻮﻟ )50 % ( ﻂﻠﺘﺨﻣ ﺪﻨﺒﻤﻫ ﺖﻓﺎﺑ يرﺎﻤﻴﺑ )50  % ( ياﺮﺑ وﺖﻳزﻮﻴﻣﻮﺗﺎﻣرد ) 100  % (دﻮﺑ .   ﻪﺠﻴﺘﻧ :يﺮﻴﮔ  ﻦﻜﻴﻟ ، ﺪﻴﺋﻮﻜﺴﻳد ﻮﺗﺎﻤﺘﻳرا سﻮﭘﻮﻟ ﺪﻨﺒﻤﻫ ﺖﻓﺎﺑ يﺎﻫ يرﺎﻤﻴﺑ ﻦﻳﺮﺘﻌﻳﺎﺷ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ رد ﻪﻓرﻮﻣ و ﺲﻳزوﺮﻠﻜﺳا. ﺪﻧدﻮﺑ آ	  دﺮﻣ ﻪﺑ نز ﺖﺒﺴﻧ08/	2  ﻪﺑ1  ﻲﻨﺳ ﻪﻫد رد نارﺎﻤﻴﺑ ﺖﻳﺮﺜﻛا و دﻮﺑ50  ﺎﺗ60   لﺎﺳ ﻲﻳﺎﻬﻧ ﺺﻴﺨﺸﺗ و ﺖﺴﻳژﻮﻟﻮﺗﺎﻣرد لوا ﻲﻗاﺮﺘﻓا ﺺﻴﺨﺸﺗ ﻦﻴﺑ ﻖﺑﺎﻄﺗ ناﺰﻴﻣ ﻦﻳﺮﺘﻤﻛ و ﻦﻳﺮﺘﺸﻴﺑ . ﺪﻨﺘﺷاد راﺮﻗ. دﻮﺑ ﺲﻳزوﺮﻠﻜﺳا ﻦﻜﻴﻟ و ﺖﻳزﻮﻴﻣﻮﺗﺎﻣرد يﺎﻫ يرﺎﻤﻴﺑ رد ﺐﻴﺗﺮﺗ ﻪﺑ ﺖﺴﻳژﻮﻟﻮﺗﺎﭘ	  تﺎﻌﻳﺎﺿ ﺖﻳﺮﺜﻛا ﻲﻜﻴﻨﻴﻠﻛ ﺮﻫﺎﻈﺗ) زﻮﺗﺎﻤﺘﻳرا كﻼﭘ ترﻮﺻ ﻪﺑ5/	28  ) ندﺮﮔ و ﺮﺳ يﺮﻴﮔرد ﻞﺤﻣ ﻦﻳﺮﺘﻌﻳﺎﺷ و دﻮﺑ ( %6/	57 . دﻮﺑ ( %  :هژاوﺪﻴﻠﻛ ﻲﺘﺳﻮﭘ تﺎﻌﻳﺎﺿ ﺪﻨﺒﻤﻫ ﺖﻓﺎﺑ يرﺎﻤﻴﺑ ، نﺎﻣﺮﻛ ،   Abstract Background: The aim of this study was to determine the prevalence of skin lesions in patients with connective tissue disease referred to the operating room of Afzalipour Hospital in Kerman, Iran. Materials and Methods: This descriptive-analytic cross-sectional study was performed on 288 patients. At first, the demographic characteristics of patients including age, sex were recorded in the checklist, then the clinical features of the skin lesions included duration of the disease, location of the lesion, clinical type of the lesion (papules, plaques, nodules and patches ...), lesion color (red, Purple, hyper or hypopigmentant) and sampling specification (final diagnosis and location of sampling) were recorded. Finally, a positive correlation between differential diagnosis of dermatologist and final diagnosis was performed by the pathologist. Data were analyzed by SPSS  25. Results: The results of this study showed that the most common connective tissue diseases in the participants in the study was Discoid Lupus Erythematosus  with a prevalence of 71,4, is the most common age group of connective tissue diseases 50 to 60 years old (24,2%). In terms of sex, the prevalence of Discoid Lupus Erythematosus  (64,5%), Lichen sclerosis  (75,7%), Systemic Lupus Erythematosus (81%), Systemic sclerosis (88,8%) and Morphea (3,8%), Subacute Cutaneous Lupus Erythematosus (60%) was more common in females than males. For the duration of the disease, the most common connective tissue disorder wasDiscoid Lupus Erythematosus (68%) for less than 6 months. Regarding the location of the disease, the most common connective tissue disorder was related to Discoid Lupus Erythematosus in head and neck (92,7%). In terms of color, the most common connective tissue disorder associated with Discoid Lupus Erythematosus was erythematous (57,3%). In the clinic, the most common connective tissue disorder associated with Discoid Lupus Erythematosus was plaque (62,9%). Also, the percentage of cases of compliance between the final diagnosis and differential diagnosis was first performed by the dermatologist for Discoid Lupus Erythematosus, 45,8% for Systemic sclerosis, 88,8% for Morphea, 56,2% for Lichen sclerosis 26,2% for sclerosis, 27,2% for Systemic Lupus Erythematosus was 81,8%, for Subacute Cutaneous Lupus Erythematosus  60% ,  for Lupus tumidus, 50% for mixed connective tissue disease 50 %, and 100% for dermatomyositis. Conclusion: In the present study, the most common diseases of the connective tissue were Discoid Lupus Erythematosus, Lichen sclerosis and Morphea. The female to male ratio was 2,08 to 1, and most of the patients were 50 to 60 years old at the age of decades. The highest and lowest rates of correlation between dermatologist diagnosis and final diagnosis were in dermatomyositis and Lichen sclerosis. The clinical manifestation of the majority of lesions was erythematous plaque (28,5%) and the most common site of head and neck involvement (57,6%).  Keywords: Skin lesions, Connective tissue disease, Kerman  

بررسی فراوانی ضایعات پوستی دربیماران با بیماری  بافت همبند  مراجعه کننده به اتاق عمل پوست بیمارستان افضلی پور کرمان از سال 1390-1396

http://eprints.kmu.ac.ir/29740/1/6931.pdf

بررسی فراوانی ضایعات پوستی دربیماران با بیماری بافت همبند مراجعه کننده به اتاق عمل پوست بیمارستان افضلی پور کرمان از سال 1390-1396

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