Study on Prevalence of TTV among Cirrhotic patients due to
Hepatitis B & C in Ahwaz University Hospitals during the Years
2004-2005
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Abstract
Background and Aims: Recently, a novel DNA virus was isolated from the serum of a
patient with post-transfusion non A-G hepatitis and named TT virus. The aim of this study
was to determine the prevalence TT virus among cirrhotic patients due to hepatitis B & C in
infection Ahwaz.
Methods: The prevalence of TTV infection was studied in 41 patients with liver cirrhosis.
TTV DNA was detected by semi-nested PCR. The plasma samples were tested for marker
hepatitis B & C by ELISA test.
Results: TT virus was detected in 17(41.46%) of the 41 patients with cirrhotic liver disease.
There were no significant difference between the subject TTV DNA in relation to sex and
age. TTV positivity in cirrhotic patient infected with hepatitis B (52.9%) was higher than in
similar patients infected with hepatitis C (47.1%).
Conclusion: TTV infection was highly prevalence in patient with cirrhotic hepatitis,
especially in those with hepatitis B virus infection