The increasing production of large tonnage of products in brewing industries continually generates lots of solid waste
which includes spent grains, surplus yeast, malt sprout and cullet. The disposal of spent grains is often a problem and
poses major health and environmental challenges, thereby making it imminently necessary to explore alternatives for its
management. This paper focuses on investigating the effects of Brewery Spent Grain formulated diet on haematological,
biochemical, histological and growth performance of Donryu rats. The rats were allocated into six dietary treatment
groups and fed on a short-term study with diet containing graded levels of spent grains from 0, 3, 6, 9, 12 and 100%
weight/weight. The outcome demonstrated that formulated diet had a positive effect on the growth performance of the
rats up to levels of 6% inclusions, while the haematological and biochemical evaluation revealed that threshold limit
should not exceed 9% of the grain. However, the histological study on the liver indicated a limit of 3% inclusion in feed
without serious adverse effect. Thus invariably showing that blend between ranges 1-3% is appropriate for the utilization
of the waste in human food without adverse effect on the liver organ. The economic advantage accruing from this waste
conversion process not only solves problem of waste disposal but also handle issues of malnutrition in feeding ration
