BMJ PUBLISHING GROUP, BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
Abstract
Background: For frequent extra-articular (systemic) manifestations of joints
inflammatory diseases are various damage of the nervous system,2 and the presence
and severity of peripheral neuropathy (PNP) have significance in the clinical
course, which incidence among these patients is 5%–10%.1 Nevertheless, many
clinical and pathogenic aspects of this peripheral neuropathy (PNP) remain
obscure.
Objectives: to evaluate the rate and clinical features of PNP in rheumatoid arthritis
(RA), chlamydia urogenital reactive arthritis (ReA), psoriatic arthritis (PA) and
ankylosing spondylitis (AS), to examine the issues of pathogenetic constructions
such changes of the nervous system, define risk factors.
Methods: The study included 416 patients with inflammatory joint diseases,
among them 131 RA patients, 101 ReA, 76 PA and 108 AS. The average age of
the examined was respectively 45, 32, 42 and 38 years, disease duration – 10, 4,
12 and 11 years, male to female ratio – 1:5, 1:1, 1:2 and 10:1
