The definition of glaucoma has changed during past century. Traditionally glaucoma was recognized as increase in intraocular pressure but today glaucoma refers to a group of multifactorial disorders which lead to progressive loss of Retinal ganglion cells. This multidimensional nature of glaucoma made it an interesting area of research. Despite of successful management of intraocular pressure, still significant number of cases progress the course of disease and end up with irreversible RGCs loss. Thanks to recent advancement in understanding of pathophysiology of glaucoma, several agents have been introduced during past decades which act through alternative mechansims other than convential mechansims. Conventionally glaucoma treated as its primary risk factor, increased in intraocular pressure. Main goal in approaching patients with glaucoma is to decrease neural loss, which this goal achieved by decrease intraocular pressure, neuroprotection and neuroregeneration. This paper reviews current pharmacological novel approaches in treatment of glaucoma.egységes, osztatlanáltalános orvosango
