A noval vaccine formulation consisting of DNA vaccine inactivated virus

Abstract

Disclosed herein is a novel vaccine formulation for prophylactic or therapeutic immunization of vertebrates against infections caused by vertebrate viruses. The said vaccine contains a min. of two components, one of which is a deoxyribonucleotide (DNA) vaccine comprising of a DNA mol. that encodes a polypeptide of the virus and the other component consisting of inactivated form of the virus. This invention can also be used to develop low cost inactivated virus-based vaccines that contain much lower amt. of the said virus than that present in similar vaccines known in the prior art. The examples focus on the methods of producing a novel vaccine compn. against the rabies virus