The process of studying heavy metal concentrations in lake sediments in order to reconstruct pollution history has been used in a variety of environments and locations. Laguna Pacucha is one in a series of metal pollution studies from Peru and Bolivia, an area with a rich history of metallurgy. Laguna Pacucha lies in the Andahuaylas region of Peru, 145 km west of Cuzco, the Inca capital, and 20 km west of Curamba, a presumed ancient smelting site. The sediment record of Laguna Pacucha reveals a metal record that dates beyond 1225 AD. A major density change ~1225 AD, concurrent with a known period of drought, inhibits the possibility of a reliable age model below this point. Increases in Zn, As, and Cu after ~1225 AD could be indicative of local copper smelting, which supports separate evidence of the Curamba archeological site (near Laguna Pacucha) as a potential copper smelting site. These concentrations drop around the time of the Spanish conquest, and then the concentrations of a number of different metals increase after ~1600 and decrease by ~1850 AD, which could indicate smelting, but more likely indicates a change in land use. Our results provide a complex record of a changing Andean environment, and indicate a need for further study in the Andahuaylas region