Driven systems of interconnected blocks with stick-slip friction capture main features of earthquake processes. The microscopic dynamics closely resemble those of spiking nerve cells. We analyze the differences in the collective behavior and introduce a class of solvable models. We prove that the models exhibit rapid phase locking, a phenomenon of particular interest to both geophysics and neurobiology. We study the dependence upon initial conditions and system parameters, and discuss implications for earthquake modeling and neural computation