Baker, Nick

Elder, Dawn

Fleming, Peter

Lawton, Beverley

MacFarlane, Melanie

McDonald, Gabrielle

Mitchell, Edwin A.

Percival, Teuila

Schlaud, Martin

Stewart, Alistair W.

Taylor, Barry

Thompson, John M. D.

Zuccollo, Jane

SummaryThis study has shown that many of the risk factors that were identified in the original New Zealand Cot Death Study (1987–1989) are still relevant today. The combination of maternal smoking in pregnancy and bed sharing is extremely hazardous for infants. Furthermore, our findings indicate that the SUDI prevention messages are still applicable today and should be reinforced. SUDI mortality could be reduced to just 7 p.a. in New Zealand (approximately one in 10,000 live births).AbstractDespite a major reduction in overall infant mortality, sudden unexpected death in infancy (SUDI) continues to be of concern in New Zealand, as the rate is high by international standards, and is even higher in indigenous Māori.AimTo identify modifiable risk factors for SUDI.MethodA three-year (1 March 2012–28 February 2015) nationwide case-control study was conducted in New Zealand.ResultsThere were 137 SUDI cases, giving a SUDI mortality rate of 0.76/1,000 live births. The rate for Māori was 1.41/1,000, Pacific 1.01/1,000 and non-Māori non-Pacific (predominantly European) 0.50/1,000. The parent(s) of 97% of the SUDI cases were interviewed. Six hundred and forty-nine controls were selected and 258 (40%) were interviewed. The two major risk factors for SUDI were: maternal smoking in pregnancy (adjusted OR=6.01, 95% CI=2.97, 12.15) and bed sharing (aOR=4.96, 95% CI=2.55, 9.64). There was a significant interaction (p=0.002) between bed sharing and antenatal maternal smoking. Infants exposed to both risk factors had a markedly increased risk of SUDI (aOR=32.8, 95% CI=11.2, 95.8) compared with infants not exposed to either risk factor. Infants not sharing the parental bedroom were also at increased risk of SUDI (aOR=2.77, 95% CI=1.45, 5.30). Just 21 cases over the three-year study were not exposed to smoking in pregnancy, bed sharing or front or side sleeping position.ConclusionThis study has shown that many of the risk factors that were identified in the original New Zealand Cot Death Study (1987–1989) are still relevant today. The combination of maternal smoking in pregnancy and bed sharing is extremely hazardous for infants. Furthermore, our findings indicate that the SUDI prevention messages are still applicable today and should be reinforced. SUDI mortality could be reduced to just seven p.a. in New Zealand (approximately one in 10,000 live births)

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The combination of bedsharing and maternal smoking leads to a greatly increased risk of sudden unexpected death in infancy:the New Zealand Nationwide SUDI case control study

http://hdl.handle.net/1983/4ff39f33-2e89-451d-95b8-f70ee30b2278

The combination of bedsharing and maternal smoking leads to a greatly increased risk of sudden unexpected death in infancy:the New Zealand Nationwide SUDI case control study

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