Köser, J.

Rossetti, Fernanda

Siegmann, Konstantin

Winkler, Martin

ZHAW Zürcher Hochschule für Angewandte Wissenschaften

Anti-Microbial Polyethylene SurfacesK. Siegmann1, F. F. Rossetti1, J. Köser2, M. Winkler11 Zurich University of Applied Sciences, Institute of Materials and Process Engineering, Technikumstrasse 9, CH-8401 Winterthur, Switzerland. 2 Hochschule für Life Sciences, Institut für Chemie und Bioanalytik, Gründenstrasse 40, CH-4132 Muttenz, SwitzerlandResearch ideasAchievements (implementation)Next stepsReferences.Rossetti, F F; Siegmann, K; Koser, J; Winkler, M; Antimicrobial Polyethylene through Melt Compounding with Quaternary Ammonium Salts. J. Appl. Pol. Sci. in preparation.To kill germs as soon as they adhere; to produce biocidal surfacesQuarternary ammonium compounds (quats) are biocidal. When mixed (compounded) with  polyethylene, quats will segregate. Quats point the head group out of the polyethylene.Quats are anchored with a long hydrocarbon chain in the matrix.Permanent biocidal       polyethylene surfaces Four newly synthesized quats and five commercial quats were investigated.A test for the biocidal activity of the new surfaces was developped.It was shown that certain quats render polyethylene biocidal and were The most promising quat was synthesized on a kilogramm scale.Adhesion Growth SpreadBacteriaTo prevent the  adhesion of germsnot washed out.The mechanical properties of the polyethylene do not deteriorate.A cross-section through a water tube with biofilm.Biofilm growth and spread on a submerged surface.Fig. 2 Dead (green) and living (red) bacteria on treated (left) and untreated (right) PEAre biocidal surfaces also biophobic, i.e., prevent the formation of biofilm?All surfaces with N+ larger than about 10 atoms/nm2 are biocidal.If surface concentration is smaller than 10 atoms/nm2, then the surface can also be biocidal.After leaching biocidal activity is retained.Dead/life staining with fluorescent dye is performed.Biocidal activity of polyethylene with quat is demonstrated.Problem: biofilm formationWinkler, M; Siegmann, K; Plastic Having a Biocidal Surface and Method for Producing Said Plastic. WO 2014/174434 A1Fig. 1 Surface concentration of head-groups (N+) as a function of nitrogen in the moleculeSurface properties

Anti-microbial polyethylene surfaces

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Anti-microbial polyethylene surfaces

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