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一种链霉菌发酵代谢产物新奥霉素的分离提取方法
Authors
周金燕
杨杰
谭红
钟娟
Publication date
27 May 2014
Publisher
Abstract
本发明公开一种链霉菌发酵代谢产物新奥霉素的分离提取方法,方法包括:首先将发酵液先加热升温至60℃,杀灭发酵液中的链霉菌活菌体,通过滤布或陶瓷微滤膜除去新奥霉素发酵液中培养基固形物和菌体杂质后,除去固形物的发酵液经大孔吸附树脂吸附处理,然后,用阳离子交换树脂吸附富集大孔吸附树脂流出液中的新奥霉素,最后,采用0.5‑5.0%氨水进行解析、浓缩,制成新奥霉素母液,或添加载体,烘干制成粉剂。本发明提供了一种新的低成本制备新型生物农药新奥霉素母药或制剂的方法
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Last time updated on 29/08/2018