Additional file 1: of CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation

Abstract

Figure S1. Generation of 2nd generation CAR.MUC1 T cells. (A) Schematic of 2nd generation CAR.MUC1 (2G) retroviral construct. (B) Co-expression of 4/7ICR and 2G CAR as detected by mOrange and anti-IgG, respectively. Summary data (right panel) shows percentage of double-positive cells (mean ± SEM, n = 4). (PPTX 298 kb