Table S1. Epidemiological features from the Spain GWAS cohort. Figure S1. Principal component analysis of the Spain GWAS cohort. Figure S2. Quantile-quantile(Q-Q) plots of observed and expected -log10(p values) of association between SNP genotype and SLE risk. Table S2. Epigenetic regulatory data associated with GRB2 risk locus. Figure S3. Regional association plot for the association with SLE risk independent of GRB2 SNP rs36023980. Figure S4. GRB2 gene expression during human B cell differentiation. (DOCX 627 kb