Additional file 3: of Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches
Figure S3. Characterization of immune cell phenotyping using marker panel 2. Cell phenotypes were defined as memory cells (CD45RO, including memory/natural killer cells CD45RO + CD57 + granzyme B−, memory/regulatory cells CD45RO + FOXP3+, memory antigen experienced cells CD45RO + PD-1+, and other CD45RO+ cells), memory/regulatory cells (CD45RO + FOXP3+), memory antigen experienced cells (CD45RO + PD-1+), activated natural killer cells (CD57 + granzyme B + CD45RO−), and antigen experienced cells (PD-1, including PD-1 + CD45RO+ and other PD-1+ cells). Each type of cell is shown as individual images by marker and by a composite image. (PPTX 103717 kb
