Additional file 3: of Pericellular collagen I coating for enhanced homing and chondrogenic differentiation of mesenchymal stem cells in direct intra-articular injection
Figure S3. In-vivo homing suspended in col. I solution. a, b BLIS analysis of luminescent distribution within left knees of New Zealand rabbits at 2 days after DIAI of luciferase-labeled MSCs or MSCs suspended in 10 ng/ml col. I solution. Red frames indicate cartilage defect (a, n = 3 in each group). Luminescent intensity of total ROI radiance within cartilage defect (red frame) calculated to reveal homing of MSCs (b). a Sagittal frozen sections of cartilage lesion site, red particles are CM-DiI-labeled MSCs (scale bar, 400 μm). (TIF 1614 kb