<p>We have developed two independent methods for measuring the one-dimensional power spectrum of the transmitted flux in the Lyman-<em>α</em> forest. The first method is based on a Fourier transform and the second on a maximum-likelihood estimator. The two methods are independent and have different systematic uncertainties. Determination of the noise level in the data spectra was subject to a new treatment, because of its significant impact on the derived power spectrum. We applied the two methods to 13 821 quasar spectra from SDSS-III/BOSS DR9 selected from a larger sample of over 60 000 spectra on the basis of their high quality, high signal-to-noise ratio (S/N), and good spectral resolution. The power spectra measured using either approach are in good agreement over all twelve redshift bins from ⟨<em>z</em>⟩ = 2.2 to ⟨<em>z</em>⟩ = 4.4, and scales from 0.001 km s<sup>-1</sup> to 0.02 km s<sup>-1</sup>. We determined the methodological andinstrumental systematic uncertainties of our measurements. We provide a preliminary cosmological interpretation of our measurements using available hydrodynamical simulations. The improvement in precision over previously published results from SDSS is a factor 2–3 for constraints on relevant cosmological parameters. For a ΛCDM model and using a constraint on <em>H</em><sub>0</sub> that encompasses measurements based on the local distance ladder and on CMB anisotropies, we infer <em>σ</em><sub>8</sub> = 0.83 ± 0.03 and<em>n</em><sub>s</sub> = 0.97 ± 0.02 based on H i absorption in the range 2.1 < <em>z</em> < 3.7.</p