TGF-β activation and inhibition in fibroblast and Capan-2 co-cultured with MLEC. Data was analyzed with Student’s t-test. Error bars are standard deviations. A) TGF-β activation inhibition with Cilengitide (0 to 10 μM). B) TGF-β activation inhibition with cRGD peptide (0 to 10 μM). C) Effects on TGF-β activation by co-culturing KAT-4 cells (Kat4, K) or Capan-2 (Capan2, C) together with MLEC reporter cells (M) on plastic dishes coated with human plasma fibronectin (HFN) or human plasma vitronectin (Vn). (TIF 8227 kb