<p>Alveolate clades are highlighted with a gray background, and their expected phylogenetic relationship is indicated by a tree structure above. Gray and white boxes indicate the presence and absence of the corresponding ortholog, respectively. The hatched boxes represent the presence of the ortholog in <i>C</i>. <i>muris</i> only and absence in <i>C</i>. <i>parvum</i> and <i>C</i>. <i>hominis</i>. The table on the left lists the gene ID for all ASAPs, along with their annotation, essentiality phenotypes (phenotype score from CRISPR/Cas9 knockout study [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2006128#pbio.2006128.ref050" target="_blank">50</a>]), and protein localization. The key for localization annotation is given below the table. ASAP, ATP synthase–associated protein; Cas9, CRISPR-associated 9; CRISPR, clustered regularly interspaced short palindromic repeat; OSCP, oligomycin sensitivity–conferring protein.</p
