Forcing persistent non-SOP expression of <i>neur</i> causes both loss and gain of SOPs.

Abstract

<p>(A) Quantification of macrochaete gain and loss on the dorsal head and thorax of flies of the genotypes indicated at right. Error bars represent SEM. (B and C) Scutellar bristle positions in 24 hr APF nota of the indicated genotypes, stained with anti-Cut antibody, show loss of the SOP with <i>neur</i> misexpression. (D-I) Uniform expression of <i>UAS-neur</i> driven by <i>tub-GAL4</i> in <i>neur</i> mutant clones using the MARCM system in either a wing imaginal disc (D-F) or a 12 hr APF notum (G-I). GFP (green in F and I) marks the territories of <i>tub>neur</i> expression; anti-Sens antibody signal (magenta in F and I) marks SOPs. Brackets in D and F mark SOP loss at the region of overlap between <i>tub>neur</i> activity and the wing margin. Sens-positive cells boxed in D are in a different focal plane from the GFP-expressing cells.</p

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