Cu-Catalyzed π‑Core Evolution of Benzoxadiazoles with Diaryliodonium Salts for Regioselective Synthesis of Phenazine Scaffolds

Abstract

The Cu-catalyzed regioselective synthesis of phenazine <i>N</i>-oxides was realized from benzoxadiazoles and diaryliodonium salts. The process was initiated by the electrophilic arylation of benzoxadiazoles with diaryliodonium salts and followed by benzocyclization reactions. The further reduction of <i>N</i>-oxides in situ to phenazine scaffolds and deviation to organic fluorescent materials were readily accomplished