The ultra-wideband (UWB) antenna is developed to cover a broad bandwidth. The UWB radio systems are interfered by the same spectrum that shared with the local bands. In this paper, two F-shaped slots on a hexagonal patch UWB antenna are demonstrated to realize a high band rejection. The symmetrical couple F-slots is notched on the hexagonal UWB patch antenna to avoid the interference and enhance the notching results at C-band. The demonstrated antenna employs a coplanar waveguide (CPW) technique to meet a fractional bandwidth of 126%. The proposed method validates several reconfigurations of the F-slot location on the demonstrated design. Six steps parametric study are considered to test the slots location. The results of the proposed antenna with slots are introduced based on analytical, simulation, and measurement. The total design size 28 mm × 43 mm × 1.6 mm is simulated by using CST Microwave Studio. The two F-slots are achieved the antenna gain of -6 dB, return loss of -1.2 dB, and VSWR of 15.2 at the rejected band of 4 GHz. The measurement results are compared with the simulation results between the three prototypes. The current distribution on the design is discussed at 2.88 GHz and 4 GHz frequencies. The radiation patterns illustrate omnidirectional of H-plane and bidirectional of E-plane. This paper validates the slots locations to enhance the notches performance and reduce the interference
