Applying persuasive system design to different cultures has been a focus of many researchers as the global medium of communication has been centered within Smartphone via applications (apps). This is due to the vast proliferation of the Smartphone and the personal attachment of users to this device in various cultures. This led designers to search for ultimate ways to target users in specific regions of the world. The basic purpose of this study was to determine the relevance of cross-cultural factors to persuasive technologies, and the acceptance and loyalty of Smartphone apps. This was achieved by examining the moderating effects of Hofstede’s six cross-cultural dimensions on the relationship between Oinas-Kukkonen and Harjumaa’s Persuasive System Design (PSD), and acceptance and loyalty. By evaluating elements of persuasive systems design and cross-cultural dimensions, from user’s perspective, against a globally popular application like WhatsApp, an instrument was devised to investigate the cross-cultural adoption and continued use of Smartphone apps. Using this instrument, surveys were conducted for this research study to identify the influencing factors that have motivated the users from Malaysia, Netherlands, Germany, and the Kingdom of Saudi Arabia to adopt and continue using this application on a daily basis. These surveys, which included responses from 488 participants, further investigated if there is one cross-cultural dimension that has more moderating effects per country. The findings indicate an agreement among WhatsApp users from all four countries about their reasons for adopting and using this app, namely: social influence (93.7 percent), reliability (83.4 percent), dialog-support via feedback (76.4 percent), ease of use (90.5 percent) and small cost (87.7 percent). The results put new perspective that the gap among cultures is narrowing. Persuasive design strategies are particularly relevant to cultures across the globe. This study can aid the research community in investing efforts into enhancing the persuasive design framework for Smartphone apps
