The main objective of this research is to produce a high concentrations of sorbitol using solid state fermentation (SSF) of meranti wood dust by bacteria Lactobacillus plantarum (BAA 793; NCIMB 8826). Before the fermentation process, meranti wood dust has been treated through physical and chemical processes for the recovery of cellulose, followed by enzymatic hydrolysis process to produce glucose. The resulting glucose is then used as the carbon sources in fermentation to produce sorbitol. Parameters studied in sorbitol production using solid-state fermentation is fermentation time (2 hours to 14 hours), moisture content (40% to 90%) and temperature (25oC to 45oC). Method one factor at a time (OFAT) conducted on all parameters to determine an appropriate range before the response surface methodology (RSM) is implemented. From this study, the results showed that the optimum condition for the production of sorbitol is at 10 hours, with 50% moisture content and temperature of 35oC where the production of sorbitol is 29.0625g/L. Results of this experiment showed that SSF produce high sorbitol than SMF
