Marine organisms are primary source of bioactive compounds for nutraceuticals industries. These bioactives can be extracted from different marine sources including animals and plants. These compounds are considered as safer alternatives to some existing synthetic drugs as they exhibit significant biological properties which contribute to their nutraceutical potential. In the present scenario, some marine derived bioactive compounds are being marketed as good and safer drugs for health and some of them are subjected under advance investigation in clinical trials. Marine bioactives include peptides, fatty acids, carbohydrates especially sulfated polysaccharides (SPs). These are useful in food industries and perform the healing functions like anti-hyperlipedimic, antioxidant, antidiabetic and these all functions contribute towards cardiac protection. Current review focuses the recent research on bioactives from different marine sources to protect one's cardiac health