Cultivation of Calocybe indica was undertaken with locally available substrates viz. paddy straw, maize stalk waste, bamboo leaves and young coconut fibre alone and various combinations with paddy straw + maize stalk (1:1 v/v), paddy straw+ saw dust (1:1 v/v), and paddy straw+ saw dust (1:2 v/v)and different casing materials suchas vermicompost, soil+ sand (1:1v/v), dried saw dust, hard paper (wet condition) and combination of tea waste+soil+ sand, saw dust +sand (1:1 v/v), tea waste+ sand (1:1 v/v) in paddy straw cultivating condition. Among the substrates, paddy straw was the best with 196.12 % biological efficiency (BE) followed by different substrate combinations but the bamboo leaves alone was recorded as substrate with lowest potential (84%) for cultivation. As casing material the spent mushroom compost (SMC) of Agaricus bisporus resulted in the highest biological efficiency (207%) followed by soil+ sand (196%), sand +saw dust (163%) but combination of tea waste+ soil + sand was inferior (151%). Saw dust gave the lowest (96.8%) biological efficiency. In conclusion the maximum biological efficiency of C. indica can be obtained by using paddy straw as a substrate encased with spent compost of button mushroom
