Additional file 7: of Cross-talk between microtubules and the linker of nucleoskeleton complex plays a critical role in the adipogenesis of human adipose-derived stem cells
Figure S7. LINC complex disruption perturbs the perinuclear organization of MTs in hASCs. Immunofluorescence analysis of sun2-knockdown hASCs and GFP control. Cells were stained for Îą-tubulin (red), SUN2 (cherry), and DNA (blue). The box area with disturbed perinuclear MT network organization (Scale bar = 20 Îźm). In siControl cells, MTs appeared to be shorter, sparser, and were changed into a vacuolar structure, while in siSUN2 cells, MTs maintained the integrity and rarely disrupted. (TIFF 1876 kb
