In vitro characterization of a new composite material for biomedical applications and 3D (bio)printing

Abstract

Study goal: The present project aims at evaluating the cytocompatibility and printability of a new composite material, based on a mixture of a new methacrylate-based monomer developed within a CTI project (18514.1 PFLS-LS) and glass-ceramic powder supplemented with co- and photo-initiators (patent in preparation). This study is the basis to demonstrate the suitability of the biomaterial, for biomedical applications, such as stent, orthopedic implants and hearing aid components, as well as for 3D (bio)printing Key findings: - Cultivation, proliferation and differentiation of three different human cell types were successfully established on composite material discs (1cm diameter, 1mm height). Biological activity was shown - The material is suitable for 3D (bio)printing, printing protocols were established - The new composite material is suitable for cell and tissue interaction in biomedical application