Additional file 1: of Blockade of sustained tumor necrosis factor in a transgenic model of progressive autoimmune encephalomyelitis limits oligodendrocyte apoptosis and promotes oligodendrocyte maturation
TNF blockade reduces astrocyte and myeloid cell reactivity during progressive EAE in GFAPγR1Δ mice. Longitudinal spinal cord sections from WT and GFAPγR1Δ mice treated with isotype control or anti-TNF mAb were stained for astrocyte (GFAP) or myeloid cell (Iba-1) reactivity at d19 and d30 as indicated. Data represents three to four separate fields per mouse with two to three mice per group. (TIF 1843 kb
